Introduction: Brain cancer treatment is notoriously difficult due to the blood-tumor barrier (BTB) that restricts the penetration of...

Introduction: Malignant glioma is a highly aggressive brain tumor with a dismal prognosis. Temozolomide (TMZ), a DNA-alkylating agent,...

Introduction: The blood-brain barrier (BBB) is crucial for maintaining the central nervous system's (CNS) environment, formed by...